Next Generation Sequencing in South Africa

Next-generation sequencing (NGS) has revolutionized the way scientists explore DNA, RNA, and genetic variations. In South Africa, this transformative technology is becoming an essential tool in medicine, agriculture, biodiversity research, and more. As demand for accurate, scalable, and cost-effective sequencing grows, CPGR is at the forefront of delivering world-class NGS and long-read sequencing services to researchers, healthcare professionals, and industry leaders.

Understanding Next Generation Sequencing

Next Generation Sequencing refers to advanced DNA sequencing technologies that allow for the rapid reading of entire genomes or specific genetic regions. Unlike traditional methods, NGS enables the sequencing of millions of fragments simultaneously, offering unparalleled speed, depth, and precision.

At CPGR, we employ both short-read and long-read sequencing platforms, ensuring flexibility and accuracy depending on the application.

What Makes NGS So Powerful?

NGS technology is:

Fast – Entire genomes can be sequenced in days instead of months.
Cost-effective – As the technology evolves, sequencing costs continue to drop.
High-throughput – Millions of DNA fragments are analyzed in parallel.
Scalable – From small research projects to large population-scale studies.

Whether you’re analyzing microbial communities, performing cancer genomics, or exploring rare genetic disorders, NGS opens up a world of possibilities.

Applications of NGS in South Africa

South Africa’s unique biodiversity and complex population structure make it an ideal region for cutting-edge genomics research. With support from CPGR, local scientists and institutions are unlocking new discoveries across many sectors:

1. Healthcare and Medical Research

NGS plays a vital role in:

Identifying genetic diseases
Personalized medicine
Cancer genomics
Infectious disease surveillance (e.g., HIV, TB, COVID-19)

For example, NGS was instrumental in tracking COVID-19 variants across South Africa, helping public health authorities respond effectively.

2. Agricultural Innovation

NGS helps improve:

Crop resistance
Animal breeding programs
Soil microbiome analysis

With climate change and food security being pressing issues, NGS in agriculture offers sustainable solutions tailored to South Africa’s unique environment.

3. Conservation Genomics

South Africa is home to extraordinary flora and fauna. NGS enables long-read sequencing of endangered species, aiding conservation programs by mapping biodiversity, understanding evolutionary history, and monitoring genetic health.

Why CPGR for NGS in South Africa?

Located in South Africa, CPGR (Centre for Proteomic and Genomic Research) is one of the continent’s leading genomics service providers. We specialize in:

NGS library preparation
High-throughput sequencing
Data analysis and bioinformatics
Customized genomic workflows

Our state-of-the-art facilities and expert team ensure your research project meets the highest global standards.

Cutting-edge Platforms We Offer

CPGR provides access to a variety of sequencing platforms including:

Illumina for high-quality short reads
Oxford Nanopore & PacBio for long read sequencing

Long read sequencing is ideal for:

Resolving complex genomic regions
Structural variant analysis
De novo genome assemblies

End-to-End Support

From sample collection and preparation to sequencing and bioinformatics interpretation, CPGR delivers a seamless NGS experience tailored to your research goals.

The Rise of Long Read Sequencing

While traditional short-read NGS remains powerful, long-read sequencing is gaining popularity due to its ability to:

Sequence full-length genes
Improve genome assembly accuracy
Detect structural variants more effectively

At CPGR, we’re proud to offer long read sequencing solutions in South Africa, enabling researchers to explore DNA with greater continuity and clarity.

How to Get Started

Whether you are a researcher, clinician, or biotech startup, CPGR simplifies access to world-class genomics tools.

Here’s how to start your NGS project with us:

Consult with our team to outline your goals
Select the right sequencing approach (short-read or long-read)
Submit samples or plan sample collection
Receive comprehensive sequencing and bioinformatics reports

All projects are handled with strict quality control, data security, and confidentiality.

Partnering for a Genomic Future

South Africa is stepping into a genomic era where data drives innovation. At CPGR, we’re proud to empower this shift by offering Next Generation Sequencing and long read sequencing with unmatched local expertise and global reliability.

By working with CPGR, you’re not just accessing technology—you’re partnering with a dedicated team passionate about pushing the boundaries of genomics in South Africa and beyond.