Next Generation Sequencing (NGS) & Long Read Sequencing in South Africa

Next Generation Sequencing

Next Generation Sequencing (NGS) and Long Read Sequencing have transformed the field of genomics, offering deeper, faster, and more detailed insights into DNA and RNA. At CPGR, we provide cutting-edge NGS solutions to research institutions, clinical labs, and biotech companies across South Africa.

Our services focus on delivering high-throughput, cost-effective sequencing, tailored to meet the demands of both academic and commercial projects.

What is Next Generation Sequencing (NGS)?

Next Generation Sequencing (NGS) is a powerful technology that enables the rapid sequencing of DNA or RNA, producing massive amounts of data in a short time. Unlike traditional Sanger sequencing, NGS processes millions of sequences simultaneously, offering:

  • High throughput
  • Increased accuracy
  • Lower cost per sample
  • Real-time data processing

In South Africa, CPGR is leading the way in applying Next Generation Sequencing NGS Long Read Sequencing technologies for precision medicine, agricultural biotechnology, and infectious disease surveillance.

Benefits of NGS & Long Read Sequencing

Long Read Sequencing, a type of NGS, is particularly useful for resolving complex genomic regions, structural variants, and repetitive sequences. Here’s why researchers and labs in South Africa are turning to CPGR for their sequencing needs:

  • Improved genome assembly
    Long reads bridge gaps in sequencing that short reads can’t, delivering complete, contiguous genomes.
  • Accurate detection of structural variants
    Long-read sequencing is ideal for identifying inversions, translocations, and duplications with high confidence.
  • Epigenetic modifications
    Some long-read sequencing platforms can detect methylation patterns directly from DNA strands.
  • Better understanding of disease mechanisms
    NGS allows deeper insights into rare genetic disorders, cancers, and infectious pathogens.

Why CPGR is the Trusted NGS Partner in South Africa

As a pioneering genomics facility in South Africa, CPGR offers comprehensive Next Generation Sequencing NGS Long Read Sequencing services to advance innovation in science and healthcare. Our core strengths include:

  • State-of-the-art platforms
    We use leading NGS systems like PacBio, Oxford Nanopore, and Illumina to provide both short and long read options.
  • Expert bioinformatics
    CPGR offers data analysis pipelines that convert raw reads into actionable insights. Our team assists with variant calling, genome assembly, annotation, and data visualisation.
  • Flexible project support
    Whether you’re a clinical researcher, a startup, or an agricultural scientist, we tailor our solutions to meet your project’s goals.
  • National and global collaborations
    CPGR is connected to global genomic networks and supports academic and clinical research institutions throughout South Africa.

Applications of NGS & Long Read Sequencing in South Africa

NGS and long-read sequencing have wide-reaching applications across multiple sectors in South Africa:

Clinical Genomics

Identify genetic mutations linked to hereditary disorders, cancers, and rare diseases. Our NGS tests empower precision diagnosis and personalised treatment.

Infectious Disease Surveillance

NGS enables rapid pathogen identification and variant tracking, crucial for managing outbreaks like COVID-19 and TB in South Africa.

Agricultural Genomics

Support breeding programs and crop improvement strategies. CPGR’s Next Generation Sequencing NGS Long Read Sequencing services enhance productivity in the agri-biotech sector.

Microbiome Studies

Explore complex microbial communities in the environment or human body using metagenomic sequencing.

How Long Read Sequencing Enhances Genomic Research

Traditional short-read technologies are powerful, but they have limitations. That’s where Long Read Sequencing steps in, offering reads that span thousands of base pairs and covering entire genes or transcripts in a single run.

This is especially important in South African research environments, where comprehensive genome assemblies are needed to study indigenous plant and animal species or to track genetic diversity in human populations.

At CPGR, our long-read capabilities eliminate the need for guesswork and deliver more complete genomic data.

NGS in South Africa: Challenges & Future Prospects

While Next Generation Sequencing NGS Long Read Sequencing is rapidly growing in South Africa, several challenges persist:

  • Infrastructure limitations in remote labs
  • Cost barriers for small research teams
  • Data storage and analysis capacity

Despite these hurdles, CPGR is working to democratise genomic access in South Africa. We provide scalable sequencing solutions and training workshops, making NGS more accessible across regions.

The future? A surge in genomics-based healthcare, climate-resilient crops, and targeted therapy research powered by NGS and Long Read Sequencing.

Partner with CPGR for NGS & Long Read Sequencing in South Africa

Whether you’re mapping a genome, studying disease progression, or exploring biodiversity, CPGR has the tools and expertise to help. With top-tier Next Generation Sequencing NGS Long Read Sequencing platforms and a team of seasoned professionals, we’re ready to partner with you on your journey into advanced genomics.

Our services are available across South Africa, including Cape Town, Johannesburg, Pretoria, and beyond.

Get Started with CPGR Today

Interested in bringing the power of Next Generation Sequencing NGS Long Read Sequencing to your research? Reach out to CPGR South Africa’s trusted name in genomics.

We offer personalised project assessments, rapid turnaround times, and competitive pricing tailored to your needs.

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