Metagenomics Sequencing: 16S vs Shotgun Explained

What Is Metagenomics Sequencing? Metagenomics sequencing has transformed the way scientists study microorganisms by allowing entire microbial communities to be analysed directly from environmental or clinical samples, without the need to culture organisms in the laboratory. Traditional microbiology depends on growing microorganisms under laboratory conditions before they can be identified. However, many microbes cannot be […]
How Long-Read Sequencing Is Transforming Metagenomics Research

Microorganisms are everywhere. They inhabit soil, oceans, rivers, plants, animals, and the human body, influencing everything from ecosystem health to disease susceptibility. Yet most microbial species cannot be easily cultured in a laboratory, making them difficult to study using traditional microbiological methods. Metagenomics has transformed this field by allowing researchers to sequence all genetic material […]
RT-PCR South Africa: Gene Expression, Genotyping and qPCR Services at CPGR

RT-PCR South Africa continues to play a critical role in modern molecular biology, clinical research, agriculture, and biotechnology. Real-Time Polymerase Chain Reaction (qPCR or RT-PCR) is one of the most sensitive and reliable methods available for detecting and quantifying nucleic acids. Unlike conventional PCR, real-time PCR measures amplification as it occurs, allowing researchers to accurately […]
GWAS in South Africa: Why African Genomes Are Reshaping Global Disease Research

GWAS South Africa is rapidly emerging as a critical frontier in global genomic science. Genome-Wide Association Studies (GWAS) is an approach to scan the genomes of large populations to identify genetic variants associated with disease risk and complex traits. Historically, GWAS has been heavily biased toward European populations. This has limited the global applicability of […]
Next Generation Sequencing South Africa: Transforming Precision Medicine in Africa

Precision medicine is transforming global healthcare, but its success in Africa depends on access to advanced genomic technologies. Next Generation Sequencing South Africa is playing a critical role in enabling this shift, allowing researchers and clinicians to generate high-resolution genomic data that supports more accurate diagnosis, targeted therapies, and improved patient outcomes. As genomics research […]
World Kidney Cancer Day: Kidney Cancer Genomics South Africa

18 June marks World Kidney Cancer Day, a global awareness initiative dedicated to improving understanding, diagnosis, treatment, and research for kidney cancer worldwide. As the global scientific community observes World Kidney Cancer Day, researchers are increasingly turning to genomics, proteomics, and bioinformatics to unlock new insights into one of the world’s most challenging cancers. Kidney […]
How Genomics is Transforming Biodiversity Research

Every species carries a story written in its DNA. From microorganisms to complex ecosystems, biodiversity forms the foundation of life on Earth. Yet today, biodiversity loss is accelerating at an unprecedented rate, driven by climate change, habitat destruction, pollution, and emerging environmental pressures. Understanding and protecting biodiversity has therefore become one of the most important […]
How Long‑Read Sequencing Is Transforming Microbiology Research in South Africa and Beyond

Microbiology research today depends on genetic insight. Whether profiling complex microbial communities via 16S rRNA and ITS targeted metabarcoding, or probing functional potential with shotgun metagenomics, genomic data is central to scientific discovery. Yet many researchers in South Africa and other under-represented regions face persistent hurdles: limited sequencing infrastructure, high costs, data analysis bottlenecks, and […]
Microarray Genotyping for Precision Medicine

Precision medicine starts with population-aware SNP genotyping. In today’s landscape of genomics and genetics research, the ability to generate high-quality, population-relevant genetic data is fundamental to discovery. Whether advancing genome-wide association studies (GWAS), building precision medicine programmes, or exploring complex disease biology, researchers require scalable, accurate, and accessible genotyping solutions. At CPGR, we provide the […]
Autism Genetics Breakthrough: How Long-Read Sequencing Is Advancing Variant Discovery

Each year on World Autism Awareness Day, observed on 2 April, global communities come together to promote awareness, inclusion, and continued research into autism spectrum conditions. Autism genetics is a rapidly evolving field that seeks to understand the complex genetic architecture underlying autism. While genetic research has long established a link between autism and genomic […]